Effect of Casein Gluten Free Snack, Nutrition Education and Level of Pb and Zn Metal on Clinical Manifestation of Autism

Background and Objective: People with autism in Medan are quite high due to the high Casein and Gluten intake, low Zn metal and high Pb metal. The aim of this study was giving Casein Gluten Free (CGF) Snacks snacks and nutritional education to reduce the symptoms of clinical manifestations of people with autism. Materials and Methods: The study was Quasi experimental with the design of post test only control group design with 4 autistic schools location in Medan. The sample was divided into 3 groups namely controls group, CGF
Snack (group 1) and CGF Snack and Nutrition Education (group 2). Analysis was carried out with Pearson correlation tests and one way
ANOVA. Results: Metal Pb was significantly associated with the occurrence of clinical manifestations (p<0.05) and had a very strong closeness (r = 0.825) and Zn metal was not significantly associated (p = 0.141). The group 2 made the most significant contribution (p<0.05) to the decrease of clinical manifestation. Conclusion: The results of the study showed that snack CGF and nutritional education were the most influential Pb metal had an effect, while Zn did not affect the clinical manifestations.